Welcome to FBMLab - a leading life science company in the field of extracellular vesicles. We offer tailored solutions with innovative laboratory analyses for both businesses and individuals.
About Extracellular Vesicles
One of the emerging research areas in biomedicine is the study of extracellular vesicles, which are small membrane-bound particles that transport various molecules and signals between cells. EVs are produced by all types of cells under different physiological and pathological conditions, and they reflect the state and function of their original cells.
EVs can transfer their cargo, such as mRNA, microRNA, DNA, and mitochondria, to recipient cells and modify their gene expression and metabolism. EVs can also display specific surface markers that can be used to identify their origin and activation status.
Therefore, EVs can play a significant role in intercellular communication and regulation of various biological processes, such as inflammation, immunity, angiogenesis, coagulation, and cancer progression.
EVs also have great potential as biomarkers for diagnosis, prognosis, and monitoring of therapy in many diseases and conditions, such as cardiovascular disease, autoimmune disease, cancer, and neurological disorders.
Analysis of extracellular vesicles
EVs have sparked increased interest in diagnostics due to their potential as biomarkers and therapeutic agents. EVs can provide valuable information about the health status and disease status. For example, EVs can reveal the presence and progression of tumors, infections, autoimmune diseases, and cardiovascular diseases.
Whether you are interested in exploring the role of EVs in basic research or developing new EV-based applications for clinical or research purposes, we can help you achieve your goals.
We offer tailor-made solutions for different types of samples (e.g., blood, urine, saliva, cerebrospinal fluid) and different phenotypes of EVs.
Study Design
The analysis of extracellular vesicles (EVs) can be tailor-made specifically for each project and purpose. After an initial consultation, a specific flow cytometry panel is designed to detect specific subgroups of EVs that may be of interest.
Our service offers a comprehensive and flexible approach to EV analysis, based on an initial consultation with the client. We can design a flow cytometry panel that can measure various parameters of EVs, such as size, concentration, surface markers, and intracellular molecules (e.g., DNA and mRNA). We can analyze virtually any type of biological fluid, such as blood, urine, cerebrospinal fluid (CSF), saliva, or breast milk.
The results of our EV analysis can be presented as a detailed report including graphs, tables, and statistics. The report can also include a discussion about the biological significance and implications of the results. Our EV analysis service can help you discover new aspects of cell-cell communication, identify new biomarkers for diseases or treatment responses, and explore the potential therapeutic uses of EVs.
If you would like to know more about our services or request a quote, please contact us today. We look forward to working with you on your exciting EV projects.
About Us
FBMLab is a leading company in consultation and high-capacity analysis of extracellular vesicles (EV). We offer a range of services, from isolation and characterization of EV to biomarker discovery. With more than 20 years of experience in the field, we have the expertise and technology to help you develop your research and applications in EV.
Fariborz Mobarrez, PhD, CEO, has more than 20 years of experience in analyzing and using EV as biomarkers in both preclinical and clinical studies. Before he started FBM Lab Konsult AB in 2017, Fariborz was a full-time researcher at the Karolinska Institute in cardiology and rheumatology. In parallel with his work as CEO, Fariborz also works as a university lecturer at Uppsala University in the field of biomedical laboratory science. Fariborz has worked on both international and national projects in cardiovascular diseases, autoimmune diseases, cancer, and neurological diseases.
FBMLab has collaborated with various universities and international pharmaceutical companies, such as H. Lundbeck, where FBMLab has a master service agreement.
We are committed to providing high-quality service and if you are interested in our services or want to learn more about EVs, contact us today.
Selected Publications
Leakage of astrocyte-derived extracellular vesicles in stress-induced exhaustion disorder: a cross-sectional study. Wallensten J, Nager A, Åsberg M, Borg K, Beser A, Wilczek A, Mobarrez F.Sci Rep. 2021 Jan 21;11(1):2009.
Electronic cigarettes containing nicotine increase endothelial and platelet derived extracellular vesicles in healthy volunteers. Mobarrez F, Antoniewicz L, Hedman L, Bosson JA, Lundbäck M.Atherosclerosis. 2020 May;301:93-100.
Microvesicles from patients with acute coronary syndrome enhance platelet aggregation. Kafian S, Wallén H, Samad BA, Mobarrez F. Scand J Clin Lab Invest. 2019 Nov;79(7):507-512.
Microparticles in the blood of patients with SLE: Size, content of mitochondria and role in circulating immune complexes. Mobarrez F, Fuzzi E, Gunnarsson I, Larsson A, Eketjäll S, Pisetsky DS, Svenungsson E. J Autoimmun. 2019 Aug;102:142-149.
Microparticles as autoantigens in systemic lupus erythematosus. Mobarrez F, Svenungsson E, Pisetsky DS. Eur J Clin Invest. 2018 Dec;48(12):e13010.